Laura, I noticed that too about chick-lit settings in LA and NYC! I think it’s got something to do with the urban “vibe” from these cities – most folks are familiar with LA either from frequent visits or constant exposure through films and TV shows. I have family in Southern California, so I’m familiar with certain parts of LA that I have visited in the past.
For what it’s worth, the first chick-lit novel that I had ever finished was mostly set in Manila, but with pivotal scenes in LA, Chicago, and Hong Kong. 🙂